Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TERT | O14746 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PIR | O00625 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | HSF1 | Q00613 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13758995 | 0.86 | KMT2A (0.47) | KMT2ATERTMAPTTP53PIR | |
| SCHEMBL428830 | 0.82 | KMT2A (0.44) | KMT2ATERTPIRBRAFGSK3B | |
| SCHEMBL13759336 | 0.79 | MAPT (0.42) | KMT2AMAPTTP53PIRBRAF | |
| SCHEMBL431018 | 0.78 | GRM4 (0.46) | KMT2ATERTMAPTTP53MEN1 | |
| SCHEMBL426551 | 0.78 | GRM4 (0.46) | KMT2ATERTMAPTTP53BRAF | |
| SCHEMBL13758989 | 0.76 | HTT (0.52) | MAPTTP53S1PR1LMNAKDR | |
| SCHEMBL3121188 | 0.76 | P2RY12 (0.42) | KMT2AMAPTTP53BRAFMEN1 | |
| SCHEMBL13759190 | 0.75 | GRM4 (0.43) | TERTMAPTTP53 | |
| SCHEMBL425931 | 0.75 | GRM4 (0.44) | KMT2AMEN1 | |
| SCHEMBL430538 | 0.74 | GRM4 (0.43) | KMT2ATERTMAPTTP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007050980-A2 | PROCESS FOR PREPARING MESYLATE SALTS OF IL-12 INHIBITORY COMPOUNDS | SYNTA PHARMACEUTICALS CORP. (US) | 2007-05-03 | — | — | WO | disclosed |