Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 16/20 | 0.54 |
| ▸ | AURKB | Q96GD4 | 10/20 | 0.49 |
| ▸ | AURKA | O14965 | 2/20 | 0.49 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.47 |
| ▸ | TTK | P33981 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 7/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8247827 | 0.87 | AURKA (0.53) | PTK6AURKBAURKAMAPKAPK5TTK | |
| SCHEMBL13954839 | 0.83 | PTK6 (0.55) | PTK6AURKBAURKAMAPKAPK5TTK | |
| SCHEMBL8426671 | 0.78 | BRD4 (0.39) | PTK6AURKATTKLCK | |
| SCHEMBL5575570 | 0.77 | MAPKAPK5 (0.58) | PTK6AURKBAURKAMAPKAPK5TTK | |
| SCHEMBL14538354 | 0.76 | PTK6 (0.52) | PTK6AURKBAURKAMAPKAPK5TTK | |
| SCHEMBL14530726 | 0.73 | PTK6 (0.56) | PTK6AURKBAURKAMAPKAPK5TTK | |
| SCHEMBL14537083 | 0.73 | PTK6 (0.56) | PTK6AURKBAURKAMAPKAPK5LCK | |
| SCHEMBL14530402 | 0.72 | MAPKAPK5 (0.58) | PTK6AURKBAURKAMAPKAPK5TTK | |
| SCHEMBL1674322 | 0.71 | MAPKAPK5 (0.63) | PTK6AURKBAURKAMAPKAPK5TTK | |
| SCHEMBL14536960 | 0.71 | MAPKAPK5 (0.62) | PTK6AURKBAURKAMAPKAPK5TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058942-A2 | IMIDAZOPYRAZINES AS PROTEIN KINASE INHIBITORS | SCHERING CORPORATION (US) | 2007-05-24 | — | — | WO | disclosed |
| WO-2007058873-A2 | IMIDAZOPYRAZINES AS CYCLIN DEPENTEND KINASE INHIBITORS | SCHERING CORPORATION (US) | 2007-05-24 | — | — | WO | disclosed |