Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CCNC | P24863 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 3/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13775010 | 0.85 | NPSR1 (0.38) | NPSR1CCNCCDK8CNR1CNR2 | |
| SCHEMBL13775011 | 0.81 | NPSR1 (0.35) | NPSR1IDH1 | |
| SCHEMBL12808519 | 0.77 | NPSR1 (0.61) | NPSR1CCNCCDK8PDE3BPDE3A | |
| SCHEMBL13774984 | 0.72 | TDP1 (0.37) | CCNCCDK8RPS6KB2TSHR | |
| SCHEMBL13775064 | 0.71 | CYP11B1 (0.37) | CCNCCDK8RPS6KB2 | |
| SCHEMBL14531013 | 0.70 | NPSR1 (0.52) | NPSR1CCNCCDK8CNR1CNR2 | |
| SCHEMBL13774982 | 0.69 | PDE4D (0.36) | CCNCCDK8RPS6KB2TSHR | |
| SCHEMBL2473673 | 0.68 | NPSR1 (0.50) | NPSR1CCNCCDK8PDE3BPDE3A | |
| SCHEMBL4190066 | 0.68 | DRD2 (0.37) | NPSR1CCNCCDK8RPS6KB2IDH1 | |
| SCHEMBL13775072 | 0.68 | HRH3 (0.34) | CCNCCDK8CNR2RPS6KB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056366-A2 | COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS | IRM LLC (BM) | 2007-05-18 | — | — | WO | disclosed |