Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | UBE2N | P61088 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1176769 | 1.00 | KDM4E (0.36) | KDM4EALDH1A1HPGDTSHRCYP2D6 | |
| SCHEMBL1176770 | 1.00 | KDM4E (0.36) | KDM4EALDH1A1HPGDTSHRCYP2D6 | |
| SCHEMBL12871697 | 0.83 | — | — | |
| SCHEMBL12885788 | 0.79 | — | — | |
| SCHEMBL12871696 | 0.78 | HSD17B10 (0.34) | KDM4EALDH1A1HPGDTSHRCYP2D6 | |
| SCHEMBL1177017 | 0.78 | HSD17B10 (0.34) | KDM4EALDH1A1HPGDTSHRCYP2D6 | |
| SCHEMBL1177014 | 0.78 | HSD17B10 (0.34) | KDM4EALDH1A1HPGDTSHRCYP2D6 | |
| SCHEMBL12871707 | 0.74 | MAPT (0.33) | KDM4EALDH1A1KMT2ANPC1MAPK1 | |
| SCHEMBL12885796 | 0.71 | ALDH1A1 (0.31) | ALDH1A1HSD17B10 | |
| SCHEMBL9153017 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1945605-B1 | PROCESS FOR PREPARING SUBSTITUTED ANISIDINES | BOEHRINGER INGELHEIM INT (DE) | 2013-01-09 | — | — | EP | disclosed |
| WO-2007053755-A1 | PROCESS FOR PREPARING SUBSTITUTED ANISIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-05-10 | — | — | WO | disclosed |