Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 13/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.40 |
| ▸ | PLA2G5 | P39877 | 3/20 | 0.40 |
| ▸ | PLA2G2E | Q9NZK7 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.37 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.37 |
| ▸ | PLA2G12B | Q9BX93 | 1/20 | 0.37 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.37 |
| ▸ | PLA2G2F | Q9BZM2 | 1/20 | 0.37 |
| ▸ | PLA2G3 | Q9NZ20 | 1/20 | 0.37 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13485088 | 0.82 | PLA2G2A (0.56) | PLA2G2APLA2G1BPLA2G10PLA2G5PLA2G2E | |
| SCHEMBL14339077 | 0.82 | GRK6 (0.48) | PLA2G2APLA2G1BALDH1A1TDP1PLA2G10 | |
| SCHEMBL13484713 | 0.82 | PLA2G2A (0.42) | PLA2G2APLA2G1BALDH1A1PLA2G10PLA2G5 | |
| SCHEMBL28108507 | 0.74 | SLC2A1 (0.47) | PLA2G2APLA2G1BTDP1MAPTSLC2A1 | |
| SCHEMBL13597693 | 0.72 | MAPT (0.42) | PLA2G2APLA2G1BALDH1A1TDP1PLA2G10 | |
| SCHEMBL14530122 | 0.72 | DDB1 (0.40) | PLA2G2APLA2G1BALDH1A1PLA2G10PLA2G5 | |
| SCHEMBL14531269 | 0.71 | PLA2G2A (0.48) | PLA2G2APLA2G1BPLA2G10PLA2G5PLA2G2E | |
| SCHEMBL21381324 | 0.70 | TDP1 (0.57) | ALDH1A1TDP1L3MBTL1MAPT | |
| SCHEMBL14514453 | 0.69 | PLA2G2A (0.46) | PLA2G2APLA2G1BTDP1PLA2G10PLA2G5 | |
| SCHEMBL14530080 | 0.69 | PLA2G2A (0.46) | PLA2G2AALDH1A1TDP1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056279-A2 | PHOSPHOLIPASE INHIBITORS, INCLUDING MULTI-VALENT PHOSPHOLIPASE INHIBITORS, AND USE THEREOF, INCLUDING AS LUMEN-LOCALIZED PHOSPHOLIPASE INHIBITORS | ILYPSA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |