Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 11/20 | 0.44 |
| ▸ | COMT | P21964 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | TBK1 | Q9UHD2 | 3/20 | 0.40 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.40 |
| ▸ | GPR6 | P46095 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | SMO | Q99835 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12833941 | 0.91 | TRPV1 (0.41) | TRPV1HDAC6TBK1HPSEGPR6 | |
| SCHEMBL12833747 | 0.90 | TRPV1 (0.42) | TRPV1HDAC6TBK1 | |
| SCHEMBL12833483 | 0.85 | PDCD1 (0.41) | HDAC6TBK1GPR6 | |
| SCHEMBL12833945 | 0.78 | WDR5 (0.39) | SCN5ASCN9AHDAC6HPSEMAPK14 | |
| SCHEMBL1761968 | 0.77 | COMT (0.46) | COMTHDAC6 | |
| SCHEMBL12833992 | 0.76 | HDAC6 (0.46) | SCN5ASCN9AHDAC6HPSEMAPK14 | |
| SCHEMBL12833823 | 0.75 | MAPT (0.46) | SCN5ASCN9AHDAC6HPSEMAPK14 | |
| SCHEMBL12833972 | 0.75 | MAPT (0.52) | HDAC6 | |
| SCHEMBL14090945 | 0.75 | NPSR1 (0.47) | HDAC6HPSEMAPK14SMO | |
| SCHEMBL12833808 | 0.74 | PARP1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056155-A1 | HETEROCYCLIC COMPOUNDS AS TYROSINE KINASE MODULATORS | CHEMBRIDGE RESEARCH LABORATORIES, INC. (US) | 2007-05-18 | — | — | WO | disclosed |