Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLPP | Q16740 | 5/20 | 0.68 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.68 |
| ▸ | TCF7 | P36402 | 2/20 | 0.68 |
| ▸ | BCL9 | O00512 | 1/20 | 0.68 |
| ▸ | TCF4 | P15884 | 1/20 | 0.68 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 14/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13430508 | 1.00 | CLPP (0.68) | CLPPCTNNB1TCF7BCL9TCF4 | |
| SCHEMBL14309837 | 0.96 | CLPP (0.66) | CLPPCTNNB1TCF7BCL9TCF4 | |
| SCHEMBL14505248 | 0.96 | CLPP (0.66) | CLPPCTNNB1TCF7BCL9TCF4 | |
| SCHEMBL14310120 | 0.95 | CLPP (0.62) | CLPPCTNNB1TCF7BCL9TCF4 | |
| SCHEMBL14308180 | 0.95 | CLPP (0.62) | CLPPCTNNB1TCF7BCL9TCF4 | |
| SCHEMBL13773636 | 0.94 | CLPP (0.60) | CLPPCTNNB1TCF7BCL9TCF4 | |
| SCHEMBL14310056 | 0.93 | CLPP (0.59) | CLPPCTNNB1TCF7BCL9TCF4 | |
| SCHEMBL14308171 | 0.93 | CLPP (0.61) | CLPPCTNNB1TCF7BCL9TCF4 | |
| SCHEMBL13773691 | 0.93 | CLPP (0.61) | CLPPCTNNB1TCF7BCL9TCF4 | |
| SCHEMBL14308185 | 0.93 | CLPP (0.61) | CLPPCTNNB1TCF7BCL9TCF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056513-A1 | α-HELIX MIMETICS AND METHODS RELATING TO THE TREATMENT OF FIBROTIC DISORDERS | INSTITUTE FOR CHEMICAL GENOMICS (US) | 2007-05-18 | — | — | WO | disclosed |