Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14344693 | 1.00 | MEN1 (0.33) | MEN1KMT2AHSD11B1BTK | |
| SCHEMBL10249079 | 1.00 | MEN1 (0.33) | MEN1KMT2AHSD11B1BTK | |
| SCHEMBL5023741 | 1.00 | MEN1 (0.33) | MEN1KMT2AHSD11B1BTK | |
| SCHEMBL5023744 | 1.00 | MEN1 (0.33) | MEN1KMT2AHSD11B1BTK | |
| SCHEMBL5023746 | 1.00 | MEN1 (0.33) | MEN1KMT2AHSD11B1BTK | |
| SCHEMBL14531582 | 1.00 | MEN1 (0.33) | MEN1KMT2AHSD11B1BTK | |
| SCHEMBL10249197 | 1.00 | MEN1 (0.33) | MEN1KMT2AHSD11B1BTK | |
| SCHEMBL14344641 | 1.00 | MEN1 (0.33) | MEN1KMT2AHSD11B1BTK | |
| SCHEMBL10249084 | 0.80 | HSD11B1 (0.40) | MEN1KMT2AHSD11B1 | |
| SCHEMBL14531578 | 0.80 | HSD11B1 (0.40) | MEN1KMT2AHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007061661-A2 | INHIBITORS OF 11-BETA-HYDROXY STEROID DEHYDROGENASE TYPE 1 | AMGEN INC. (US) | 2007-05-31 | — | — | WO | disclosed |