Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | AGXT | P21549 | 2/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6810293 | 0.89 | APLNR (0.33) | IDO1AGXTAPLNRALDH1A1CYP3A4 | |
| SCHEMBL14533020 | 0.84 | CA1 (0.31) | — | |
| SCHEMBL14567496 | 0.83 | APLNR (0.37) | IDO1AGXTAPLNRALDH1A1 | |
| SCHEMBL13378245 | 0.82 | APLNR (0.33) | IDO1AGXTAPLNR | |
| SCHEMBL13378243 | 0.81 | APLNR (0.37) | IDO1AGXTAPLNRCYP3A4CYP2C19 | |
| SCHEMBL13378244 | 0.81 | IDO1 (0.35) | IDO1AGXTAPLNRALDH1A1CYP3A4 | |
| SCHEMBL13378221 | 0.79 | APLNR (0.33) | IDO1AGXTAPLNR | |
| SCHEMBL14253541 | 0.79 | — | — | |
| SCHEMBL5997883 | 0.78 | CA1 (0.33) | APLNR | |
| SCHEMBL5997888 | 0.78 | CA1 (0.33) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7214708-B2 | Synthetic discodermolide analogs | KOSAN BIOSCIENCES INCORPORATED (US) | 2007-05-08 | — | — | US | disclosed |