Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CDC25B | P30305 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10801730 | 0.84 | IDO1 (0.59) | IDO1ALDH1A1CDC25BCASP6RCE1 | |
| SCHEMBL27736403 | 0.81 | ALDH1A1 (0.72) | IDO1ALDH1A1CDC25BCASP6RCE1 | |
| SCHEMBL27716557 | 0.81 | ALDH1A1 (0.52) | IDO1ALDH1A1CDC25BCASP6RCE1 | |
| SCHEMBL15133540 | 0.78 | IDO1 (0.75) | IDO1ALDH1A1CDC25BCASP6RCE1 | |
| SCHEMBL30156557 | 0.78 | IDO1 (0.69) | IDO1ALDH1A1CDC25BCASP6RCE1 | |
| SCHEMBL15131699 | 0.78 | IDO1 (0.69) | IDO1ALDH1A1CDC25BCASP6RCE1 | |
| SCHEMBL10796899 | 0.77 | KAT8 (0.58) | IDO1ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL8960584 | 0.76 | IDO1 (0.67) | IDO1ALDH1A1CDC25BCASP6RCE1 | |
| SCHEMBL8006518 | 0.75 | IDO1 (1.00) | IDO1ALDH1A1CDC25BCASP6RCE1 | |
| SCHEMBL29475880 | 0.75 | IDO1 (1.00) | IDO1ALDH1A1CDC25BCASP6RCE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223786-B2 | 2-aminonaphthalene derivatives and related glycogen phosphorylase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-05-29 | — | — | US | disclosed |