Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1431699 | 0.83 | ALDH1A1 (0.53) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL1431420 | 0.83 | ALDH1A1 (0.53) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL6171023 | 0.82 | ALDH1A1 (0.47) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL6171017 | 0.82 | ALDH1A1 (0.47) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL765785 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL6171404 | 0.79 | ALDH1A1 (0.47) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL6171397 | 0.79 | ALDH1A1 (0.47) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL2797778 | 0.79 | MEN1 (0.55) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL2797777 | 0.79 | MEN1 (0.55) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL8699211 | 0.78 | TTR (0.49) | ALDH1A1KMT2AMAPTMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007062308-A2 | HOMO- AND HETEROCYCLIC COMPOUNDS SUITABLE AS CETP INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-05-31 | — | — | WO | disclosed |