Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 12/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL760289 | 0.83 | CETP (0.55) | CETPCHRM4 | |
| SCHEMBL758239 | 0.82 | CETP (0.48) | CETPCHRM4GAA | |
| SCHEMBL13491799 | 0.81 | CETP (0.68) | CETPACHECHRM4FAAHEPHX2 | |
| SCHEMBL761589 | 0.80 | POLB (0.56) | CETPGAA | |
| SCHEMBL13491795 | 0.80 | CETP (0.67) | CETPACHECHRM4FAAHEPHX2 | |
| SCHEMBL13094020 | 0.80 | CETP (0.51) | CETP | |
| SCHEMBL759529 | 0.79 | HTT (0.53) | CETPGAA | |
| SCHEMBL3068675 | 0.79 | CETP (0.51) | CETPGAA | |
| SCHEMBL762013 | 0.79 | CETP (0.51) | CETPGAA | |
| SCHEMBL13093995 | 0.78 | FKBP1A (0.52) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007062308-A2 | HOMO- AND HETEROCYCLIC COMPOUNDS SUITABLE AS CETP INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-05-31 | — | — | WO | disclosed |