Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.60 |
| ▸ | MMP9 | P14780 | 2/20 | 0.60 |
| ▸ | CA12 | O43570 | 2/20 | 0.60 |
| ▸ | CA1 | P00915 | 2/20 | 0.60 |
| ▸ | CA2 | P00918 | 2/20 | 0.60 |
| ▸ | CA9 | Q16790 | 2/20 | 0.60 |
| ▸ | MMP1 | P03956 | 1/20 | 0.60 |
| ▸ | MMP3 | P08254 | 1/20 | 0.60 |
| ▸ | MMP8 | P22894 | 1/20 | 0.60 |
| ▸ | MMP13 | P45452 | 1/20 | 0.60 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4850159 | 0.85 | MMP2 (0.42) | MMP2MMP9CA12CA1CA2 | |
| SCHEMBL9800121 | 0.85 | MMP2 (0.42) | MMP2MMP9CA12CA1CA2 | |
| SCHEMBL3935383 | 0.85 | MMP2 (0.42) | MMP2MMP9CA12CA1CA2 | |
| SCHEMBL3430638 | 0.85 | MMP2 (0.42) | MMP2MMP9CA12CA1CA2 | |
| SCHEMBL4285508 | 0.82 | MMP2 (0.60) | MMP2MMP9CA12CA1CA2 | |
| SCHEMBL2938943 | 0.82 | MMP2 (0.60) | MMP2MMP9CA12CA1CA2 | |
| SCHEMBL1987041 | 0.82 | MMP2 (0.60) | MMP2MMP9CA12CA1CA2 | |
| SCHEMBL2940123 | 0.82 | MMP2 (0.60) | MMP2MMP9CA12CA1CA2 | |
| SCHEMBL530223 | 0.82 | MMP2 (0.60) | MMP2MMP9CA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL20959222 | 0.80 | MMP2 (0.58) | MMP2MMP9CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007062314-A2 | HETEROCYCLIC CETP INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-05-31 | — | — | WO | disclosed |