Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 20/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1182987 | 0.88 | CETP (0.53) | CETPKCNH2 | |
| SCHEMBL1184059 | 0.85 | CETP (0.64) | CETPKCNH2 | |
| SCHEMBL1184057 | 0.85 | CETP (0.64) | CETPKCNH2 | |
| SCHEMBL14455525 | 0.84 | CETP (0.66) | CETPKCNH2 | |
| SCHEMBL14455547 | 0.84 | CETP (0.66) | CETPKCNH2 | |
| SCHEMBL12871548 | 0.83 | CETP (0.72) | CETPKCNH2 | |
| SCHEMBL1182970 | 0.82 | CETP (0.81) | CETP | |
| SCHEMBL1183820 | 0.82 | CETP (0.79) | CETPKCNH2 | |
| SCHEMBL14455517 | 0.81 | CETP (0.68) | CETPKCNH2 | |
| SCHEMBL1184561 | 0.81 | CETP (0.68) | CETPKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007062314-A2 | HETEROCYCLIC CETP INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-05-31 | — | — | WO | disclosed |