Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.83 |
| ▸ | APEX1 | P27695 | 3/20 | 0.83 |
| ▸ | APAF1 | O14727 | 2/20 | 0.83 |
| ▸ | LMNA | P02545 | 2/20 | 0.83 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.83 |
| ▸ | TSHR | P16473 | 1/20 | 0.83 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.83 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.83 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.83 |
| ▸ | MAPT | P10636 | 4/20 | 0.82 |
| ▸ | ABCC4 | O15439 | 3/20 | 0.82 |
| ▸ | CNR1 | P21554 | 1/20 | 0.82 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.82 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.81 |
| ▸ | MMP2 | P08253 | 1/20 | 0.81 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.63 |
| ▸ | HTR2C | P28335 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | PPARG | P37231 | 2/20 | 0.61 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6079725 | 0.94 | TDP1 (0.80) | TDP1APEX1APAF1LMNAL3MBTL1 | |
| SCHEMBL1405936 | 0.94 | TDP1 (0.80) | TDP1APEX1APAF1LMNAL3MBTL1 | |
| SCHEMBL13071965 | 0.94 | TDP1 (0.80) | TDP1APEX1APAF1LMNAL3MBTL1 | |
| SCHEMBL12809842 | 0.94 | TDP1 (0.80) | TDP1APEX1APAF1LMNAL3MBTL1 | |
| SCHEMBL1405938 | 0.94 | TDP1 (0.80) | TDP1APEX1APAF1LMNAL3MBTL1 | |
| SCHEMBL1405797 | 0.94 | TDP1 (0.80) | TDP1APEX1APAF1LMNAL3MBTL1 | |
| SCHEMBL6079741 | 0.94 | TDP1 (0.80) | TDP1APEX1APAF1LMNAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL5515645 | 0.93 | TDP1 (0.82) | TDP1APEX1APAF1LMNAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL3547739 | 0.93 | TDP1 (0.82) | TDP1APEX1APAF1LMNAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL1405969 | 0.93 | TDP1 (0.82) | TDP1APEX1APAF1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070111947-A1 | Fibrin targeted therapeutics | MCMURRY THOMAS J | 2007-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070111947-A1 | Fibrin targeted therapeutics | FGB, F13B, F2 | TDP1 2605/4885APEX1 3332/4885APAF1 135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.