Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.66 |
| ▸ | HTR2B | P41595 | 3/20 | 0.66 |
| ▸ | HTR2C | P28335 | 2/20 | 0.66 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.57 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.57 |
| ▸ | DRD3 | P35462 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.49 |
| ▸ | ACP3 | P15309 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30600480 | 0.85 | TP53 (0.65) | HTR2AHTR2BHTR2CSIGMAR1ADRA2C | |
| SCHEMBL779665 | 0.85 | TP53 (0.65) | HTR2AHTR2BHTR2CSIGMAR1ADRA2C | |
| SCHEMBL27887086 | 0.83 | TP53 (0.53) | HTR2AHTR2BHTR2CSIGMAR1ADRA2C | |
| SCHEMBL2659237 | 0.81 | HTR2A (0.77) | HTR2AHTR2BHTR2CSIGMAR1ADRA2C | |
| SCHEMBL17771951 | 0.81 | HTR2A (0.66) | HTR2AHTR2BHTR2CSIGMAR1ADRA2C | |
| SCHEMBL4624620 | 0.81 | HTR2A (0.66) | HTR2AHTR2BHTR2CSIGMAR1ADRA2C | |
| SCHEMBL9439891 | 0.81 | HTR2A (0.66) | HTR2AHTR2BHTR2CSIGMAR1ADRA2C | |
| SCHEMBL25215174 | 0.80 | TP53 (0.71) | HTR2AHTR2BHTR2CTP53TSHR | |
| SCHEMBL18888417 | 0.80 | HTR2A (0.74) | HTR2AHTR2BHTR2CSIGMAR1ADRA2C | |
| SCHEMBL16379333 | 0.80 | TP53 (0.71) | HTR2AHTR2BHTR2CTP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070111947-A1 | Fibrin targeted therapeutics | MCMURRY THOMAS J | 2007-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070111947-A1 | Fibrin targeted therapeutics | FGB, F13B, F2 | HTR2A 4735/4885HTR2B 4517/4885HTR2C 4704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.