Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 11/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.40 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14535385 | 0.84 | ACKR3 (0.62) | ACKR3CNR2TP53LMNA | |
| SCHEMBL14535539 | 0.83 | CNR2 (0.58) | ACKR3CNR2TP53LMNA | |
| SCHEMBL13068981 | 0.83 | ACKR3 (0.55) | ACKR3CNR2TP53 | |
| SCHEMBL13069478 | 0.82 | ACKR3 (0.57) | ACKR3CNR2TP53LMNASAE1 | |
| SCHEMBL1072749 | 0.82 | ACKR3 (0.62) | ACKR3CNR2TP53LMNACNR1 | |
| SCHEMBL1074238 | 0.82 | ACKR3 (0.57) | ACKR3CNR2TP53LMNACNR1 | |
| SCHEMBL12706975 | 0.82 | ACKR3 (0.57) | ACKR3CNR2TP53LMNASAE1 | |
| SCHEMBL13069039 | 0.80 | ACKR3 (0.55) | ACKR3CNR2TP53LMNASAE1 | |
| SCHEMBL1022698 | 0.80 | LMNA (0.63) | ACKR3CNR2TP53LMNA | |
| SCHEMBL1076030 | 0.79 | ACKR3 (0.62) | ACKR3CNR2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007059108-A2 | SUBSTITUTED QUINOLONES AND METHODS OF USE | CHEMOCENTRYX, INC. (US) | 2007-05-24 | — | — | WO | disclosed |