Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14535952 | 0.77 | ALDH1A1 (0.60) | ALDH1A1KMT2ALMNAL3MBTL1HTT | |
| SCHEMBL11991820 | 0.75 | ALDH1A1 (0.54) | ALDH1A1KMT2ALMNAL3MBTL1HTT | |
| SCHEMBL11991819 | 0.73 | ALDH1A1 (0.49) | ALDH1A1KMT2ALMNAMEN1POLB | |
| SCHEMBL11147764 | 0.73 | POLB (0.52) | ALDH1A1KMT2ALMNAHTTPKM | |
| SCHEMBL2476165 | 0.73 | ALDH1A1 (1.00) | ALDH1A1KMT2ALMNAL3MBTL1HTT | |
| SCHEMBL13167999 | 0.72 | TSHR (0.57) | ALDH1A1KMT2ALMNAMEN1GAA | |
| SCHEMBL11991816 | 0.72 | TSHR (0.57) | ALDH1A1KMT2ALMNAMEN1GAA | |
| SCHEMBL8354607 | 0.72 | MAPT (0.35) | ALDH1A1KMT2ALMNAL3MBTL1HTT | |
| SCHEMBL6881427 | 0.71 | ALDH1A1 (0.59) | ALDH1A1KMT2ALMNAL3MBTL1HTT | |
| SCHEMBL5759194 | 0.71 | ALDH1A1 (0.58) | ALDH1A1KMT2ALMNAL3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1442040-B1 | BRIDGED BICYCLE (1,4) BENZODIAZEPINE VASOPRESSIN RECEPTOR ANTAGONISTS | ORTHO MCNEIL PHARM INC (US) | 2007-05-23 | — | — | EP | disclosed |