Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | KHK | P50053 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1637989 | 1.00 | TDP1 (0.35) | TDP1CRHR1KDM4EALDH1A1LMNA | |
| SCHEMBL1636119 | 0.89 | TDP1 (0.37) | TDP1CRHR1KDM4EALDH1A1MAPT | |
| SCHEMBL1637509 | 0.85 | CRHR1 (0.48) | TDP1CRHR1PDE10AKHK | |
| SCHEMBL1637162 | 0.84 | CRHR1 (0.33) | CRHR1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL1637854 | 0.83 | TDP1 (0.40) | TDP1CRHR1KDM4E | |
| SCHEMBL1637184 | 0.82 | CRHR1 (0.37) | TDP1CRHR1KDM4EMAPTPDE10A | |
| SCHEMBL1637055 | 0.81 | CRHR1 (0.35) | CRHR1KDM4EALDH1A1 | |
| SCHEMBL12535024 | 0.81 | CRHR1 (0.35) | CRHR1 | |
| SCHEMBL1637778 | 0.81 | TDP1 (0.32) | TDP1CRHR1KDM4E | |
| SCHEMBL12593376 | 0.81 | CRHR1 (0.41) | TDP1CRHR1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1787992-A1 | Pyrrolopyrimidine and pyrrolopyridine derivatives substituted with cyclic amino group | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2007-05-23 | — | — | EP | disclosed |