SCHEMBL14536738

SCHEMBL14536738

Bc1cnc2c(SC)nc(CCCOC)cn12

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14538364 0.86 TLR7 (0.37) TLR7
SCHEMBL14537056 0.85 TLR7 (0.36) TLR7
SCHEMBL14507470 0.85 TLR7 (0.36) TLR7
SCHEMBL14507471 0.78 TTK (0.39) TLR7
SCHEMBL14507469 0.74 TLR7 (0.38) TLR7
SCHEMBL14507465 0.64 TTK (0.38)
SCHEMBL14507473 0.61 TTK (0.37) TLR7
SCHEMBL13693181 0.60 TTK (0.31)
SCHEMBL16273378 0.58 HRH4 (0.56) TLR7
SCHEMBL13573945 0.56 KDM4E (0.43) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007056468-A1 METHODS FOR INHIBITING PROTEIN KINASES SCHERING CORPORATION (US) 2007-05-18 WO disclosed