Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13155404 | 0.82 | TTK (0.31) | TTK | |
| SCHEMBL13954633 | 0.78 | — | — | |
| SCHEMBL9938786 | 0.75 | TTK (0.52) | TTK | |
| SCHEMBL14537057 | 0.73 | TTK (0.42) | TTK | |
| SCHEMBL13693180 | 0.67 | L3MBTL1 (0.38) | — | |
| SCHEMBL20882141 | 0.66 | KDM4E (0.35) | — | |
| SCHEMBL14538465 | 0.66 | TTK (0.46) | TTK | |
| SCHEMBL23782086 | 0.65 | HTR6 (0.32) | — | |
| SCHEMBL8427840 | 0.65 | TTK (0.34) | TTK | |
| SCHEMBL12298578 | 0.64 | TTK (0.74) | TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009097233-A9 | IMIDAZOPYRAZINES AS PROTEIN KINASE INHIBITORS | SCHERING CORPORATION (US) | 2009-09-24 | — | — | WO | disclosed |
| WO-2008057512-A2 | IMIDAZOPYRAZINES AS PROTEIN KINASE INHIBITORS | SCHERING CORPORATION (US) | 2008-05-15 | — | — | WO | disclosed |