Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | DAO | P14920 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4607774 | 0.90 | MCL1 (0.46) | KMT2AMEN1ALDH1A1CYP2C9CNR1 | |
| SCHEMBL14507412 | 0.76 | DAO (0.41) | KMT2AMEN1ALDH1A1CNR2NPY5R | |
| SCHEMBL28225381 | 0.73 | DAO (0.56) | KMT2AMEN1ALDH1A1MAPTDAO | |
| SCHEMBL14507360 | 0.71 | DAO (0.57) | KMT2AMEN1ALDH1A1MAPTDAO | |
| SCHEMBL14507372 | 0.68 | MAPT (0.43) | KMT2AMEN1ALDH1A1CYP2C9GBA1 | |
| SCHEMBL14507410 | 0.68 | MCL1 (0.40) | KMT2AMEN1ALDH1A1CNR2MAPT | |
| SCHEMBL15881071 | 0.65 | MCL1 (0.53) | KMT2AMEN1ALDH1A1MAPTDAO | |
| SCHEMBL4395470 | 0.64 | LMNA (0.40) | KMT2AMEN1ALDH1A1CYP2C9MAPT | |
| SCHEMBL4395465 | 0.64 | LMNA (0.40) | KMT2AMEN1ALDH1A1CYP2C9MAPT | |
| SCHEMBL3686019 | 0.64 | NPSR1 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056468-A1 | METHODS FOR INHIBITING PROTEIN KINASES | SCHERING CORPORATION (US) | 2007-05-18 | — | — | WO | disclosed |