SCHEMBL14538017

SCHEMBL14538017

NOCC(=O)NCC1CCCCC1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 2/20 0.52
CYP2D6 P10635 1/20 0.51
HPGD P15428 1/20 0.51
ALDH1A1 P00352 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
LMNA P02545 1/20 0.49
CA2 P00918 2/20 0.49
CA12 O43570 1/20 0.49
CA1 P00915 1/20 0.49
MMP1 P03956 1/20 0.49
MMP2 P08253 1/20 0.49
MMP3 P08254 1/20 0.49
MMP9 P14780 1/20 0.49
MMP8 P22894 1/20 0.49
CA9 Q16790 1/20 0.49
MAPT P10636 1/20 0.47
PTBP1 P26599 1/20 0.47
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
KMT2A Q03164 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12765276 0.81 HPGD (0.58) EPHX1CYP2D6HPGDALDH1A1SMN1; SMN2
SCHEMBL12765275 0.79 HPGD (0.56) EPHX1CYP2D6HPGDALDH1A1SMN1; SMN2
SCHEMBL10702291 0.79 CYP2D6 (0.61) EPHX1CYP2D6HPGDALDH1A1SMN1; SMN2
Bromide SCHEMBL9464503 0.77 CYP2D6 (0.59) EPHX1CYP2D6HPGDALDH1A1SMN1; SMN2
SCHEMBL15224105 0.77 TDP1 (0.57) EPHX1CYP2D6HPGDALDH1A1SMN1; SMN2
SCHEMBL30852953 0.76 HPGD (0.50) EPHX1HPGDALDH1A1SMN1; SMN2LMNA
SCHEMBL22197123 0.76 EPHX1 (0.59) EPHX1CYP2D6HPGDALDH1A1SMN1; SMN2
SCHEMBL17787740 0.76 EPHX1 (0.59) EPHX1CYP2D6HPGDALDH1A1SMN1; SMN2
SCHEMBL2937238 0.76 EPHX1 (0.59) EPHX1CYP2D6HPGDALDH1A1SMN1; SMN2
SCHEMBL15224107 0.76 CYP2D6 (0.58) EPHX1CYP2D6HPGDALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007059116-A2 GELDANAMYCIN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF ABRAXIS BIOSCIENCE, INC. (US) 2007-05-24 WO disclosed