Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10370757 | 0.85 | ALOX15 (0.53) | HPGDKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL12765275 | 0.81 | HPGD (0.56) | HPGDKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL12765276 | 0.80 | HPGD (0.58) | HPGDKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL9130760 | 0.78 | ALDH1A1 (0.36) | HPGDKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL27411895 | 0.77 | ALDH1A1 (0.48) | HPGDKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL14538017 | 0.76 | EPHX1 (0.52) | HPGDKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL9967995 | 0.75 | EPHX1 (0.53) | HPGDKMT2AMEN1EPHX1NPC1 | |
| SCHEMBL5968680 | 0.74 | EPHX1 (0.57) | KMT2AEPHX1NPC1RAB9ACA12 | |
| SCHEMBL28440139 | 0.74 | TDP1 (0.55) | HPGDKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL27761346 | 0.74 | EPHX1 (0.44) | HPGDKMT2AEPHX1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117794896-A | Protease inhibitors for the treatment of coronavirus infections | 斯克里普斯研究学院 | 2024-03-29 | — | — | CN | disclosed |