Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 10/20 | 0.45 |
| ▸ | BRD4 | O60885 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | YES1 | P07947 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14507591 | 0.88 | ANPEP (0.41) | TTKMAPK1AURKBNTRK1YES1 | |
| SCHEMBL14536776 | 0.87 | MERTK (0.41) | TTKMAPK1AURKBNTRK1YES1 | |
| SCHEMBL8241305 | 0.85 | TTK (0.42) | TTKMAPK1AURKBNTRK1YES1 | |
| SCHEMBL8246875 | 0.85 | TTK (0.43) | TTKMAPK1AURKBNTRK1YES1 | |
| SCHEMBL14508090 | 0.84 | TTK (0.40) | TTKAURKBFGFR1FGFR3 | |
| SCHEMBL14507631 | 0.82 | TTK (0.39) | TTKAURKB | |
| SCHEMBL14507582 | 0.82 | AURKB (0.43) | AURKB | |
| SCHEMBL14507603 | 0.82 | AURKB (0.39) | TTKMAPK1AURKBNTRK1YES1 | |
| SCHEMBL14536767 | 0.82 | TTK (0.40) | TTKAURKBFGFR1FGFR3 | |
| SCHEMBL14536800 | 0.82 | AURKB (0.39) | TTKAURKBFGFR1FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058942-A2 | IMIDAZOPYRAZINES AS PROTEIN KINASE INHIBITORS | SCHERING CORPORATION (US) | 2007-05-24 | — | — | WO | disclosed |