Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14539268 | 0.94 | KDM4E (0.46) | MEN1KMT2ARAB9AKDM4EMAPT | |
| SCHEMBL2172884 | 0.81 | ALDH1A1 (0.44) | MEN1KMT2ARAB9AKDM4EMAPT | |
| SCHEMBL31472659 | 0.77 | HPGD (0.47) | MEN1KMT2ARAB9AKDM4EMAPT | |
| SCHEMBL31472654 | 0.77 | SMN1; SMN2 (0.49) | KMT2ARAB9AMAPTCYP1A2CYP2D6 | |
| SCHEMBL14539264 | 0.75 | MAPT (0.44) | MEN1KMT2ARAB9AKDM4EMAPT | |
| SCHEMBL31472651 | 0.75 | MAPT (0.71) | MEN1KMT2ARAB9AKDM4EMAPT | |
| SCHEMBL4963462 | 0.74 | GAA (0.48) | MEN1KMT2ARAB9AKDM4EMAPT | |
| SCHEMBL27551581 | 0.74 | MAPT (0.50) | MEN1KMT2ARAB9AKDM4EMAPT | |
| SCHEMBL27926889 | 0.72 | KMT2A (0.41) | MEN1KMT2AKDM4EMAPTCYP1A2 | |
| Naphthylamine SCHEMBL27936711 | 0.71 | ALDH1A1 (0.47) | MEN1KMT2ARAB9AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101177410-A | Method for synthesizing 2-substituted enamine or enamides | UNIV ZHEJIANG TECHNOLOGY (CN) | 2008-05-14 | — | — | CN | disclosed |
| WO-2007057658-A1 | PALLADIUM CATALYSED HECK ARYLATION OR VINYLATION OF 1-SUBSTITUTED OLEFINS | THE UNIVERSITY OF LIVERPOOL (GB) | 2007-05-24 | — | — | WO | disclosed |
| CN-1271050-C | Process for preparing 2-substituted enamine or enoyl amine | UNIV ZHEJIANG TECHNOLOGY (CN) | 2006-08-23 | — | — | CN | disclosed |
| CN-1634883-A | Process for preparing 2-substituted enamine or enoyl amine | UNIV ZHEJIANG TECHNOLOGY (CN) | 2005-07-06 | — | — | CN | disclosed |