Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 11/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 5/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27541323 | 1.00 | CTSK (0.47) | CTSKCYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL14539642 | 1.00 | CTSK (0.47) | CTSKCYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL20608551 | 0.92 | CTSK (0.46) | CTSKCYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL11169650 | 0.92 | CTSK (0.46) | CTSKCYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL27370835 | 0.92 | CTSK (0.46) | CTSKCYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL22382062 | 0.89 | CTSK (0.48) | CTSKCYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL13263354 | 0.89 | CTSK (0.44) | CTSKCYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL22186263 | 0.88 | CTSK (0.43) | CTSKCYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL11165568 | 0.88 | CTSK (0.46) | CTSKCYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL8461423 | 0.87 | CTSK (0.47) | CTSKCYP1A2CYP2C9CYP2C19HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007044893-A2 | COMPOUNDS AND METHODS FOR INHIBITING HEPATITIS C VIRAL REPLICATION | INTERMUNE, INC. (US) | 2007-04-19 | — | — | WO | disclosed |