Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR2 | P21802 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 5/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 5/20 | 0.43 |
| ▸ | KIT | P10721 | 2/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31678916 | 0.88 | FGFR2 (0.61) | FGFR2PDGFRAKDRMETKIT | |
| SCHEMBL14098962 | 0.88 | FGFR2 (0.61) | FGFR2PDGFRAKDRMETKIT | |
| SCHEMBL2064387 | 0.88 | FGFR2 (0.61) | FGFR2PDGFRAKDRMETKIT | |
| SCHEMBL12663540 | 0.86 | KDR (0.43) | FGFR2PDGFRAKDRMETPDGFRB | |
| SCHEMBL1889944 | 0.86 | MAOB (0.46) | FGFR2GAAMAPTMAOAMAOB | |
| SCHEMBL12410606 | 0.84 | FGFR2 (0.43) | FGFR2GAAMAPTMAOAMAOB | |
| SCHEMBL13980801 | 0.82 | PDGFRA (0.60) | FGFR2PDGFRAKDRPDGFRB | |
| SCHEMBL14540936 | 0.81 | PDGFRA (0.45) | FGFR2PDGFRAKDRKITPDGFRB | |
| SCHEMBL12663519 | 0.81 | PDGFRA (0.51) | FGFR2PDGFRAKDRPDGFRB | |
| SCHEMBL2178142 | 0.80 | XDH (0.41) | MAOBKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1777218-A1 | Process for the preparation of 4-phenoxy quinoline derivatives | Eisai R&D Management Co., Ltd. (JP) | 2007-04-25 | — | — | EP | disclosed |