Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 6/20 | 0.45 |
| ▸ | MAPK9 | P45984 | 6/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 2/20 | 0.36 |
| ▸ | CASP6 | P55212 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1892053 | 0.87 | MAPK8 (0.48) | MAPK8MAPK9PDGFRAKDRALDH1A1 | |
| SCHEMBL1893697 | 0.86 | MAPK8 (0.41) | MAPK8MAPK9PDGFRAKDRALDH1A1 | |
| SCHEMBL1893195 | 0.82 | MAPK8 (0.45) | MAPK8MAPK9PDGFRAKDRALDH1A1 | |
| SCHEMBL1896778 | 0.80 | MAPK8 (0.43) | MAPK8MAPK9PDGFRAKDRALDH1A1 | |
| SCHEMBL13627231 | 0.77 | PDGFRA (0.50) | PDGFRAKDR | |
| SCHEMBL12663468 | 0.74 | NPC1 (0.49) | MAPK8MAPK9ALDH1A1MAPTNPC1 | |
| SCHEMBL1894465 | 0.73 | EGFR (0.40) | PDGFRAKDREGFR | |
| SCHEMBL1894775 | 0.73 | PDGFRA (0.45) | PDGFRAKDREGFRMEN1KMT2A | |
| SCHEMBL12503619 | 0.71 | EGFR (0.41) | PDGFRAKDREGFRTDP1EHMT2 | |
| SCHEMBL1893712 | 0.70 | KDR (0.46) | PDGFRAKDREGFREHMT2EHMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1777218-A1 | Process for the preparation of 4-phenoxy quinoline derivatives | Eisai R&D Management Co., Ltd. (JP) | 2007-04-25 | — | — | EP | disclosed |