Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | F2R | P25116 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4793588 | 1.00 | EPHX1 (0.42) | EPHX1ALDH1A1EPHX2SMN1; SMN2LMNA | |
| SCHEMBL4794135 | 0.92 | EPHX1 (0.46) | EPHX1ALDH1A1SMN1; SMN2LMNANPSR1 | |
| SCHEMBL14540867 | 0.92 | EPHX1 (0.46) | EPHX1ALDH1A1SMN1; SMN2LMNANPSR1 | |
| SCHEMBL4793633 | 0.91 | EPHX1 (0.45) | EPHX1ALDH1A1SMN1; SMN2LMNANPSR1 | |
| SCHEMBL4767981 | 0.88 | EPHX1 (0.43) | EPHX1ALDH1A1SMN1; SMN2LMNANPSR1 | |
| SCHEMBL4767944 | 0.87 | EPHX1 (0.56) | EPHX1ALDH1A1EPHX2SMN1; SMN2LMNA | |
| SCHEMBL4770967 | 0.87 | EPHX1 (0.47) | EPHX1ALDH1A1SMN1; SMN2LMNANPSR1 | |
| SCHEMBL5441881 | 0.87 | EPHX1 (0.56) | EPHX1ALDH1A1EPHX2SMN1; SMN2LMNA | |
| SCHEMBL4767897 | 0.86 | EPHX1 (0.49) | EPHX1ALDH1A1SMN1; SMN2LMNANPSR1 | |
| SCHEMBL5437855 | 0.86 | EPHX1 (0.52) | EPHX1ALDH1A1SMN1; SMN2LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007038138-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2007-04-05 | — | — | WO | disclosed |