Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | BCL2 | P10415 | 3/20 | 0.52 |
| ▸ | BECN1 | Q14457 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | XDH | P47989 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14540721 | 0.91 | ALDH1A1 (0.66) | ALDH1A1MAPTMEN1POLBKMT2A | |
| SCHEMBL14540778 | 0.86 | ALDH1A1 (0.56) | ALDH1A1POLBBCL2BECN1CA1 | |
| SCHEMBL14540875 | 0.84 | CA1 (0.71) | ALDH1A1MAPTHTTBCL2BECN1 | |
| SCHEMBL23052349 | 0.81 | POLB (0.66) | ALDH1A1POLBKMT2AXDHPTGS2 | |
| SCHEMBL14541080 | 0.81 | KMT2A (0.60) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL16740632 | 0.77 | MEN1 (0.72) | ALDH1A1MAPTMEN1POLBKMT2A | |
| SCHEMBL23268895 | 0.77 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2ABCL2BECN1 | |
| SCHEMBL14541152 | 0.76 | HTT (0.57) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL14540876 | 0.76 | MAPT (0.73) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL14541215 | 0.76 | ALDH1A1 (0.55) | ALDH1A1MEN1POLBKMT2ABCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007038425-A2 | ANTI-VIRAL COMPOUINDS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2007-04-05 | — | — | WO | disclosed |