Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.68 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.68 |
| ▸ | ERBB3 | P21860 | 2/20 | 0.68 |
| ▸ | KDR | P35968 | 2/20 | 0.68 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.68 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | APC | P25054 | 2/20 | 0.64 |
| ▸ | CA1 | P00915 | 3/20 | 0.61 |
| ▸ | CA2 | P00918 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | TERT | O14746 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14540795 | 0.89 | NPSR1 (0.73) | EGFRERBB2ERBB3KDRPTK2 | |
| SCHEMBL14540788 | 0.86 | EGFR (0.67) | EGFRERBB2PKMAPCCA1 | |
| SCHEMBL14540886 | 0.84 | MEN1 (0.83) | CA1CA2KMT2AMEN1NPSR1 | |
| SCHEMBL28409452 | 0.82 | CA12 (0.64) | EGFRERBB2ERBB3KDRPTK2 | |
| SCHEMBL14540884 | 0.82 | KMT2A (0.87) | CA1CA2KMT2AMEN1NPSR1 | |
| SCHEMBL14541214 | 0.79 | MEN1 (0.76) | CA1CA2KMT2AMEN1NPSR1 | |
| SCHEMBL28414052 | 0.78 | CA12 (0.65) | EGFRERBB2ERBB3KDRPTK2 | |
| SCHEMBL14541074 | 0.77 | KMT2A (0.82) | PKMCA1CA2KMT2AMEN1 | |
| SCHEMBL14541073 | 0.75 | KMT2A (0.69) | PKMCA1CA2KMT2AMEN1 | |
| SCHEMBL28020452 | 0.74 | EGFR (0.77) | EGFRERBB2ERBB3KDRPTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007038425-A2 | ANTI-VIRAL COMPOUINDS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2007-04-05 | — | — | WO | disclosed |