Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | BCL2 | P10415 | 1/20 | 0.59 |
| ▸ | BECN1 | Q14457 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14541076 | 0.92 | PKM (0.60) | KMT2AMEN1ALDH1A1PKMMAPT | |
| SCHEMBL25560057 | 0.85 | BCL2 (0.83) | PKMBCL2BECN1 | |
| SCHEMBL30370016 | 0.85 | BCL2 (0.83) | PKMBCL2BECN1 | |
| SCHEMBL14541074 | 0.85 | KMT2A (0.82) | KMT2AMEN1ALDH1A1PKMMAPT | |
| SCHEMBL14540884 | 0.83 | KMT2A (0.87) | KMT2AMEN1ALDH1A1MAPTNPC1 | |
| SCHEMBL14540886 | 0.81 | MEN1 (0.83) | KMT2AMEN1ALDH1A1MAPTNPC1 | |
| SCHEMBL25417750 | 0.80 | BCL2 (0.68) | KMT2AMEN1BCL2BECN1CA1 | |
| SCHEMBL14541077 | 0.79 | MEN1 (0.55) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL14540890 | 0.78 | BCL2 (0.68) | PKMBCL2BECN1CA1CA2 | |
| SCHEMBL25416384 | 0.78 | BCL2 (0.68) | KMT2AMEN1ALDH1A1PKMBCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007038425-A2 | ANTI-VIRAL COMPOUINDS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2007-04-05 | — | — | WO | disclosed |