Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | TGM2 | P21980 | 9/20 | 0.54 |
| ▸ | TGM1 | P22735 | 8/20 | 0.54 |
| ▸ | F13A1 | P00488 | 7/20 | 0.54 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2954213 | 0.86 | TSHR (0.63) | CYP2C19TSHRGAAMEN1KMT2A | |
| SCHEMBL6237772 | 0.85 | MEN1 (0.61) | CYP2C19TSHRGAAMEN1KMT2A | |
| SCHEMBL7393652 | 0.84 | MEN1 (0.76) | CYP2C19TSHRGAAMEN1KMT2A | |
| SCHEMBL4814264 | 0.84 | MEN1 (0.76) | CYP2C19TSHRGAAMEN1KMT2A | |
| SCHEMBL3970912 | 0.84 | MEN1 (0.76) | CYP2C19TSHRGAAMEN1KMT2A | |
| SCHEMBL379160 | 0.84 | MEN1 (0.76) | CYP2C19TSHRGAAMEN1KMT2A | |
| SCHEMBL13269785 | 0.83 | MEN1 (0.59) | CYP2C19TSHRGAAMEN1KMT2A | |
| SCHEMBL15011579 | 0.82 | MEN1 (0.73) | CYP2C19TSHRGAAMEN1KMT2A | |
| Bicarbonate SCHEMBL4357688 | 0.82 | MEN1 (0.73) | CYP2C19TSHRGAAMEN1KMT2A | |
| SCHEMBL10064223 | 0.82 | TGM2 (0.70) | CYP2C19TSHRGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007039580-A1 | IMIDAZOLYL-SUBSTITUTED BENZOPHENONE COMPOUNDS | NYCOMED GMBH (DE) | 2007-04-12 | — | — | WO | disclosed |
| WO-2007039578-A1 | IMIDAZOLYL-SUBSTITUTED AZABENZOPHENONE COMPOUNDS | NYCOMED GMBH (DE) | 2007-04-12 | — | — | WO | disclosed |
| WO-2007039581-A1 | IMIDAZOLYL-SUBSTITUTED DIAZABENZOPHENONE COMPOUNDS | NYCOMED GMBH (DE) | 2007-04-12 | — | — | WO | disclosed |