Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR2 | P21802 | 3/20 | 0.54 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.49 |
| ▸ | KDR | P35968 | 2/20 | 0.49 |
| ▸ | KIT | P10721 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17486951 | 0.86 | FGFR2 (0.48) | FGFR2PDGFRAKDRPDGFRB | |
| SCHEMBL12663582 | 0.81 | PDGFRA (0.60) | FGFR2PDGFRAKDRPDGFRB | |
| SCHEMBL17486952 | 0.81 | PDGFRA (0.47) | FGFR2PDGFRAKDRPDGFRB | |
| SCHEMBL13980699 | 0.78 | PDGFRA (0.45) | FGFR2PDGFRAKDRKITPDGFRB | |
| SCHEMBL17117826 | 0.78 | FGFR2 (0.78) | FGFR2PDGFRAKDRKITEGFR | |
| SCHEMBL19633787 | 0.78 | FGFR2 (0.48) | FGFR2PDGFRAKDRKITEGFR | |
| SCHEMBL31060325 | 0.78 | FGFR2 (0.78) | FGFR2PDGFRAKDRKITEGFR | |
| SCHEMBL19196875 | 0.76 | PDGFRA (0.56) | FGFR2PDGFRAKDRPDGFRB | |
| SCHEMBL17489704 | 0.75 | PDGFRA (0.65) | FGFR2PDGFRAKDRPDGFRB | |
| SCHEMBL25466495 | 0.74 | FGFR2 (0.60) | FGFR2PDGFRAKDRKITPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1777218-A1 | Process for the preparation of 4-phenoxy quinoline derivatives | Eisai R&D Management Co., Ltd. (JP) | 2007-04-25 | — | — | EP | disclosed |