Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR2 | P21802 | 2/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.46 |
| ▸ | KIT | P10721 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | BAX | Q07812 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7463576 | 0.81 | APP (0.52) | FGFR2PDGFRAKDRALKALDH1A1 | |
| SCHEMBL22659349 | 0.81 | EGFR (0.57) | FGFR2PDGFRAKITKDRALK | |
| SCHEMBL18754151 | 0.81 | KDM4E (0.50) | PDGFRAKDRALKKDM4EALDH1A1 | |
| SCHEMBL25466495 | 0.80 | FGFR2 (0.60) | FGFR2PDGFRAKITKDR | |
| SCHEMBL1897179 | 0.80 | ERBB2 (0.55) | FGFR2KDRKDM4EALDH1A1EGFR | |
| SCHEMBL12004509 | 0.79 | PDGFRA (0.57) | PDGFRAKDRALKKCNH2 | |
| SCHEMBL7465060 | 0.79 | APP (0.50) | FGFR2PDGFRAKDRALDH1A1HPGD | |
| SCHEMBL7465843 | 0.79 | MAPT (0.55) | PDGFRAKDRALKALDH1A1HPGD | |
| SCHEMBL13467427 | 0.79 | MPO (0.47) | FGFR2PDGFRAKDRALKKCNH2 | |
| SCHEMBL7461569 | 0.79 | LMNA (0.49) | KDRALDH1A1HPGDHSD17B10EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198196-A1 | QUINOLINE DERIVATIVE HAVING ANTI-TUMOR ACTIVITY | 王子厚 | 2017-11-23 | — | — | WO | disclosed |