Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 13/20 | 0.41 |
| ▸ | EGFR | P00533 | 4/20 | 0.39 |
| ▸ | GAK | O14976 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.39 |
| ▸ | FLT1 | P17948 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | ILK | Q13418 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25827013 | 0.84 | KDM1A (0.50) | KDM1AEGFRGAKFGFR1FLT1 | |
| SCHEMBL14540937 | 0.76 | SRC (0.44) | KDM1AEGFRGAKFGFR1FLT1 | |
| SCHEMBL3688152 | 0.72 | MAOA (0.52) | EGFRFGFR1FLT1KDRILK | |
| SCHEMBL12663478 | 0.71 | FLT1 (0.46) | KDM1AEGFRGAKFGFR1FLT1 | |
| SCHEMBL1496287 | 0.70 | PDGFRB (0.57) | EGFRGAKRIPK2 | |
| SCHEMBL5052304 | 0.69 | FGFR1 (0.54) | KDM1AEGFRGAKFGFR1FLT1 | |
| SCHEMBL29736268 | 0.69 | EHMT2 (0.60) | KDM1AEGFRGAKFGFR1FLT1 | |
| SCHEMBL2748495 | 0.69 | FLT1 (0.54) | KDM1AEGFRGAKFGFR1FLT1 | |
| SCHEMBL30465547 | 0.69 | FLT1 (0.54) | KDM1AEGFRGAKFGFR1FLT1 | |
| SCHEMBL12503594 | 0.69 | PDGFRB (0.47) | EGFRGAKRIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1777218-A1 | Process for the preparation of 4-phenoxy quinoline derivatives | Eisai R&D Management Co., Ltd. (JP) | 2007-04-25 | — | — | EP | disclosed |