Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 19/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 18/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.58 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5212671 | 0.91 | OPRD1 (0.63) | OPRD1OPRM1KCNH2ABCB11OPRK1 | |
| SCHEMBL5212289 | 0.86 | OPRD1 (0.66) | OPRD1OPRM1KCNH2ABCB11OPRK1 | |
| SCHEMBL5216436 | 0.86 | OPRD1 (0.63) | OPRD1OPRM1KCNH2ABCB11OPRK1 | |
| SCHEMBL5757468 | 0.85 | OPRD1 (0.69) | OPRD1OPRM1KCNH2ABCB11OPRK1 | |
| SCHEMBL5212356 | 0.84 | OPRD1 (0.65) | OPRD1OPRM1KCNH2ABCB11OPRK1 | |
| SCHEMBL5212842 | 0.84 | OPRD1 (0.65) | OPRD1OPRM1KCNH2ABCB11OPRK1 | |
| SCHEMBL5213772 | 0.83 | OPRD1 (0.66) | OPRD1OPRM1KCNH2ABCB11OPRK1 | |
| SCHEMBL5522849 | 0.82 | OPRD1 (0.74) | OPRD1OPRM1KCNH2ABCB11OPRK1 | |
| SCHEMBL6109824 | 0.82 | OPRD1 (0.78) | OPRD1OPRM1KCNH2ABCB11OPRK1 | |
| SCHEMBL5215882 | 0.81 | OPRD1 (0.62) | OPRD1OPRM1KCNH2ABCB11OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567496-B1 | PHENYL-PIPERIDIN-4-YLIDENE-METHYL-BENZAMIDE DERIVATIVES FOR THE TREATMENT OF PAIN OR GASTROINTESTINAL DISORDERS | ASTRAZENECA AB (SE) | 2007-04-11 | — | — | EP | disclosed |