Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 5/20 | 0.72 |
| ▸ | ESRRG | P62508 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.46 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | CCND1 | P24385 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4987436 | 0.84 | MLYCD (1.00) | MLYCDESRRGNR1H3NR1H2 | |
| SCHEMBL13431498 | 0.83 | MLYCD (0.79) | MLYCDESRRGMEN1KMT2ACYP2C9 | |
| SCHEMBL12133560 | 0.76 | MLYCD (0.72) | MLYCDESRRGMEN1KMT2AMCHR1 | |
| SCHEMBL257847 | 0.74 | MLYCD (0.69) | MLYCDESRRGMEN1KMT2AMCHR1 | |
| SCHEMBL13181408 | 0.73 | MLYCD (0.64) | MLYCDMEN1KMT2AROCK2ROCK1 | |
| SCHEMBL27891608 | 0.71 | MLYCD (0.65) | MLYCDESRRGMEN1KMT2ACYP2C9 | |
| SCHEMBL2945131 | 0.71 | MLYCD (1.00) | MLYCDMEN1KMT2ANR1H3NR1H2 | |
| SCHEMBL177498 | 0.71 | MLYCD (0.64) | MLYCDESRRGCYP2C9CYP2C19GRIA2 | |
| SCHEMBL3230674 | 0.70 | MLYCD (0.78) | MLYCDMEN1KMT2ANR1H3 | |
| SCHEMBL6631811 | 0.70 | MLYCD (0.60) | MLYCDESRRGKMT2AMCHR1ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1353662-B1 | METHODS FOR THE TREATMENT OF DISEASES USING MALONYL-COA DECARBOX YLASE INHIBITORS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2007-04-18 | — | — | EP | disclosed |