Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | CCR2 | P41597 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.30 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4769808 | 1.00 | EPHX1 (0.36) | EPHX1CCR2SMN1; SMN2LMNANPSR1 | |
| SCHEMBL4769795 | 1.00 | EPHX1 (0.36) | EPHX1CCR2SMN1; SMN2LMNANPSR1 | |
| SCHEMBL14540867 | 0.84 | EPHX1 (0.46) | EPHX1SMN1; SMN2LMNANPSR1KMT2A | |
| SCHEMBL4794135 | 0.84 | EPHX1 (0.46) | EPHX1SMN1; SMN2LMNANPSR1KMT2A | |
| Hydrochloric Acid SCHEMBL4777658 | 0.83 | EPHX1 (0.38) | EPHX1CCR2SMN1; SMN2LMNANPSR1 | |
| SCHEMBL4778533 | 0.83 | F2R (0.38) | EPHX1CCR2SMN1; SMN2LMNANPSR1 | |
| SCHEMBL4835577 | 0.83 | F2R (0.38) | EPHX1CCR2SMN1; SMN2LMNANPSR1 | |
| SCHEMBL14540692 | 0.83 | F2R (0.38) | EPHX1CCR2SMN1; SMN2LMNANPSR1 | |
| SCHEMBL4793633 | 0.83 | EPHX1 (0.45) | EPHX1SMN1; SMN2LMNANPSR1KMT2A | |
| SCHEMBL4769678 | 0.82 | EPHX1 (0.39) | EPHX1SMN1; SMN2LMNANPSR1ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007038138-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2007-04-05 | — | — | WO | disclosed |