Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4778533 | 1.00 | F2R (0.38) | F2RCCR2EPHX1KMT2AALDH1A1 | |
| SCHEMBL14540692 | 1.00 | F2R (0.38) | F2RCCR2EPHX1KMT2AALDH1A1 | |
| SCHEMBL4794135 | 0.86 | EPHX1 (0.46) | EPHX1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL14540867 | 0.86 | EPHX1 (0.46) | EPHX1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL4793633 | 0.85 | EPHX1 (0.45) | EPHX1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL14540971 | 0.83 | EPHX1 (0.36) | CCR2EPHX1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL4769795 | 0.83 | EPHX1 (0.36) | CCR2EPHX1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL4769808 | 0.83 | EPHX1 (0.36) | CCR2EPHX1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL4767981 | 0.82 | EPHX1 (0.43) | EPHX1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL4793588 | 0.81 | EPHX1 (0.42) | F2REPHX1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1931652-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007038138-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2007-04-05 | — | — | WO | disclosed |