Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 16/20 | 0.36 |
| ▸ | PDE7B | Q9NP56 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14541660 | 0.92 | PDE7A (0.32) | PDE7AAGTR1 | |
| SCHEMBL13343387 | 0.90 | AGTR1 (0.34) | MEN1KMT2AAGTR1 | |
| SCHEMBL3528907 | 0.90 | AGTR1 (0.34) | MEN1KMT2AAGTR1 | |
| SCHEMBL3525435 | 0.83 | MDM2 (0.32) | AGTR1 | |
| SCHEMBL14541899 | 0.83 | PDE7A (0.36) | PDE7APDE7BPDE4DTP53 | |
| SCHEMBL3529354 | 0.81 | AGTR1 (0.34) | AGTR1 | |
| SCHEMBL13343421 | 0.81 | AGTR1 (0.34) | AGTR1 | |
| SCHEMBL13343390 | 0.79 | AGTR1 (0.32) | AGTR1 | |
| SCHEMBL3530415 | 0.79 | AGTR1 (0.32) | AGTR1 | |
| SCHEMBL3527881 | 0.78 | AGTR1 (0.34) | MEN1KMT2AAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007039177-A2 | PHENYL- AND PYRIDINYL- 1, 2 , 4 - OXADIAZOLONE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | SANOFI-AVENTIS (DE) | 2007-04-12 | — | — | WO | disclosed |