Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 12/20 | 0.43 |
| ▸ | GGPS1 | O95749 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | PNLIP | P16233 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29497740 | 0.81 | FDPS (0.36) | FDPSGGPS1 | |
| Orthosiphonol SCHEMBL29532734 | 0.78 | FDPS (0.42) | FDPSGGPS1TSHRALDH1A1CYP3A4 | |
| SCHEMBL18290368 | 0.72 | FDPS (0.43) | FDPSGGPS1TSHRALDH1A1CYP3A4 | |
| Taiwaniaquinol B SCHEMBL18105238 | 0.71 | USP2 (0.37) | FDPSGGPS1TSHRALDH1A1CYP3A4 | |
| Taiwaniaquinol E SCHEMBL31237185 | 0.71 | USP2 (0.37) | FDPSGGPS1TSHRALDH1A1CYP3A4 | |
| Taiwaniaquinol B SCHEMBL31237215 | 0.71 | USP2 (0.37) | FDPSGGPS1TSHRALDH1A1CYP3A4 | |
| SCHEMBL6658577 | 0.69 | FDPS (0.80) | FDPSGGPS1ALDH1A1CYP3A4MAPT | |
| Cryptojaponol SCHEMBL18290238 | 0.66 | FDPS (0.60) | FDPSGGPS1TSHRALDH1A1CYP3A4 | |
| Cryptojaponol SCHEMBL13532267 | 0.66 | FDPS (0.60) | FDPSGGPS1TSHRALDH1A1CYP3A4 | |
| Cryptojaponol SCHEMBL30600453 | 0.66 | FDPS (0.60) | FDPSGGPS1TSHRALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007038875-A1 | CCR5 RECEPTOR ANTAGONIST MOLECULES | AVANCE PHARMA INC. (CA) | 2007-04-12 | — | — | WO | disclosed |