Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 20/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15146127 | 1.00 | HRH4 (0.53) | HRH4HRH3 | |
| SCHEMBL13153140 | 0.86 | HRH4 (0.53) | HRH4HRH3 | |
| SCHEMBL14545856 | 0.84 | CHEK1 (0.40) | HRH4HRH3 | |
| SCHEMBL11930824 | 0.83 | HRH4 (0.49) | HRH4HRH3 | |
| SCHEMBL11930818 | 0.83 | HRH4 (0.49) | HRH4HRH3 | |
| SCHEMBL14050863 | 0.81 | SUV39H2 (0.49) | — | |
| SCHEMBL11930825 | 0.80 | CDK2 (0.47) | HRH4HRH3 | |
| SCHEMBL14050954 | 0.77 | SUV39H2 (0.44) | — | |
| SCHEMBL11930827 | 0.77 | CDK2 (0.48) | HRH4HRH3 | |
| SCHEMBL13845460 | 0.77 | CDK2 (0.50) | HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007044441-A2 | USE OF PYRAZOLO [1 , 5 -A] PYRIMIDINE DERIVATIVES FOR INHIBITING PROTEIN KINASES METHODS FOR INHIBITING PROTEIN KINASES | SCHERING CORPORATION (US) | 2007-04-19 | — | — | WO | disclosed |