Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 20/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14543100 | 0.86 | HRH4 (0.53) | HRH4HRH3 | |
| SCHEMBL15146127 | 0.86 | HRH4 (0.53) | HRH4HRH3 | |
| SCHEMBL11930837 | 0.83 | HRH4 (0.49) | HRH4HRH3 | |
| SCHEMBL13153479 | 0.77 | HRH4 (0.45) | HRH4HRH3 | |
| SCHEMBL14545856 | 0.71 | CHEK1 (0.40) | HRH4HRH3 | |
| SCHEMBL15393808 | 0.71 | HRH4 (0.51) | HRH4HRH3 | |
| SCHEMBL15393799 | 0.71 | HRH4 (0.51) | HRH4HRH3 | |
| SCHEMBL28173499 | 0.71 | HRH4 (0.77) | HRH4HRH3 | |
| SCHEMBL14516590 | 0.70 | HRH4 (0.51) | HRH4HRH3 | |
| SCHEMBL606210 | 0.70 | HRH4 (1.00) | HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010124009-A2 | FULLY HUMAN ANTI-VEGF ANTIBODIES AND METHODS OF USING | SCHERING CORPORATION (US) | 2010-10-28 | — | — | WO | disclosed |
| WO-2008130569-A1 | NOVEL PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS | SCHERING CORPORATION (US) | 2008-10-30 | — | — | WO | disclosed |