Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 16/20 | 0.71 |
| ▸ | OPRL1 | P41146 | 15/20 | 0.71 |
| ▸ | OPRK1 | P41145 | 15/20 | 0.71 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | HTR7 | P34969 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10316251 | 0.85 | OPRM1 (0.69) | OPRM1OPRL1OPRK1 | |
| SCHEMBL181682 | 0.83 | OPRM1 (1.00) | OPRM1OPRL1OPRK1HTR2AHTR7 | |
| SCHEMBL2554375 | 0.83 | OPRM1 (0.69) | OPRM1OPRL1OPRK1 | |
| SCHEMBL1859950 | 0.81 | OPRM1 (1.00) | OPRM1OPRL1OPRK1HTR2AHTR7 | |
| SCHEMBL14542901 | 0.81 | OPRM1 (0.70) | OPRM1OPRL1OPRK1 | |
| SCHEMBL12219050 | 0.80 | OPRM1 (0.63) | OPRM1OPRL1OPRK1 | |
| SCHEMBL11930767 | 0.80 | OPRM1 (0.76) | OPRM1OPRL1OPRK1 | |
| SCHEMBL28667548 | 0.80 | OPRM1 (0.80) | OPRM1OPRL1OPRK1 | |
| SCHEMBL9837438 | 0.80 | OPRM1 (0.75) | OPRM1OPRL1OPRK1 | |
| SCHEMBL1864606 | 0.79 | OPRM1 (0.66) | OPRM1OPRL1OPRK1HTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007044441-A2 | USE OF PYRAZOLO [1 , 5 -A] PYRIMIDINE DERIVATIVES FOR INHIBITING PROTEIN KINASES METHODS FOR INHIBITING PROTEIN KINASES | SCHERING CORPORATION (US) | 2007-04-19 | — | — | WO | disclosed |