Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.61 |
| ▸ | MEN1 | O00255 | 8/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14521787 | 0.84 | MEN1 (0.54) | KMT2AMEN1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL10921326 | 0.80 | MEN1 (0.55) | KMT2AMEN1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL197282 | 0.80 | SMN1; SMN2 (0.67) | KMT2AMEN1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL11700132 | 0.80 | KMT2A (0.67) | KMT2AMEN1SMN1; SMN2RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL9486219 | 0.78 | SMN1; SMN2 (0.64) | KMT2AMEN1SMN1; SMN2RAB9ANPC1 | |
| Methane SCHEMBL27454317 | 0.78 | SMN1; SMN2 (0.64) | KMT2AMEN1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL83796 | 0.78 | MEN1 (0.80) | KMT2AMEN1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL11242722 | 0.77 | GCGR (0.54) | KMT2AMEN1SMN1; SMN2MAPTLMNA | |
| Phosphonic Acid SCHEMBL10340566 | 0.77 | KMT2A (0.58) | KMT2AMEN1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL9518238 | 0.77 | GAA (0.71) | KMT2AMEN1SMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070078146-A1 | Antiinflamamtory agents; antiarthritic agents; inflammatory bowel disorders; multiple sclerosis; asthma | PHARMACIA CORPORATION | 2007-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070078146-A1 | Antiinflamamtory agents; antiarthritic agents; inflammatory bowel disorders; multiple sclerosis; asthma | MAPK1, MAPK3, MAPK4 | KMT2A 1449/4885MEN1 3032/4885SMN1; SMN2 2049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.