Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | HTT | P42858 | 3/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.66 |
| ▸ | MEN1 | O00255 | 6/20 | 0.66 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | CA12 | O43570 | 1/20 | 0.64 |
| ▸ | BRD4 | O60885 | 1/20 | 0.64 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.64 |
| ▸ | CA1 | P00915 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | MB | P02144 | 1/20 | 0.64 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.64 |
| ▸ | CA3 | P07451 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | RARG | P13631 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9486219 | 0.98 | SMN1; SMN2 (0.64) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL14384589 | 0.94 | SMN1; SMN2 (0.79) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 | |
| Phosphonic Acid SCHEMBL10340566 | 0.92 | KMT2A (0.58) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL4743252 | 0.90 | ALDH1A1 (0.70) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL10921326 | 0.88 | MEN1 (0.55) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL11656245 | 0.88 | KMT2A (0.69) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL861674 | 0.87 | SMN1; SMN2 (0.84) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL8896479 | 0.87 | EPHX1 (0.57) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL10922613 | 0.87 | PKM (0.72) | KMT2AMEN1ALDH1A1CA12CA1 | |
| Hydrochloric Acid SCHEMBL8896309 | 0.85 | EPHX1 (0.56) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 613 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290353-A | Preparation method of stable isotope labeled diazepam | 司法鉴定科学研究院 | 2024-07-05 | — | — | CN | claimed |
| CN-117347533-B | Method for detecting related substances of compound paracetamol and renin tablets for children | 山东则正医药技术有限公司 | 2024-04-19 | — | — | CN | claimed |
| CN-117347533-A | Method for detecting related substances of compound paracetamol and renin tablets for children | 山东则正医药技术有限公司 | 2024-01-05 | — | — | CN | claimed |
| CN-113999130-B | Preparation method of o-nitroanilide compound | 湖北工业大学 | 2023-09-29 | — | — | CN | claimed |
| CN-115996911-A | Substituted N-phenylacetamides having P2X4 receptor antagonistic activity | 拜耳公司 | 2023-04-21 | — | — | CN | claimed |
| CN-111606820-B | Preparation method of N-iodobenzene-N-phenylamide compound | 湖北工业大学 | 2023-03-31 | — | — | CN | claimed |
| CN-114832799-B | Preparation and application of carbon-point bonded silica gel chromatographic stationary phase based on eutectic solvent | 中国科学院兰州化学物理研究所 | 2023-02-28 | — | — | CN | claimed |
| CN-115097049-A | Method for determining related substances in pediatric paracetamol, atificial cow-bezoar and chlorphenamine maleate granules | 广西壮族自治区食品药品检验所 | 2022-09-23 | — | — | CN | claimed |
| US-20220274926-A1 | IMMUNOREGULATORY AGENTS | FLEXUS BIOSCIENCES INC (US) | 2022-09-01 | — | — | US | claimed |
| CN-114965754-A | Method for detecting related substances and bacteriostatic agent in acetaminophen tablet | 陕西必康制药集团控股有限公司 | 2022-08-30 | — | — | CN | claimed |
| WO-2007070818-A1 | SIX-MEMBERED HETEROCYCLES USEFUL AS SERINE PROTEASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-06-21 | — | — | WO | claimed |
| WO-2007070816-A2 | THIOPHENE DERIVATIVES AS FACTOR XIA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-06-21 | — | — | WO | claimed |
| US-20060058553-A1 | Novel bicyclic hydroxamates as inhibitors of histone deacetylase | AXYS PHARMACEUTICALS, INC. (US) | 2006-03-16 | — | — | US | claimed |
| EP-1472216-A2 | NOVEL BICYCLIC HYDROXAMATES AS INHIBITORS OF HISTONE DEACETYLASE | Axys Pharmaceuticals (US) | 2004-11-03 | — | — | EP | claimed |
| US-6794383-B2 | Heart muscular cell apoptosis inhibitors and remedies/preventives for heart diseases | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2004-09-21 | — | — | US | claimed |
| WO-2003066579-A2 | NOVEL BICYCLIC HYDROXAMATES AS INHIBITORS OF HISTONE DEACETYLASE | AXYS PHARMACEUTICALS (US) | 2003-08-14 | — | — | WO | claimed |
| EP-0470669-B1 | Preparation of fluorophenols, fluorohalophenols, N-acylfluoroanilines, and N-acylfluorohaloanilines | DOWELANCO (US) | 1997-11-12 | — | — | EP | claimed |
| EP-0470669-A2 | Preparation of fluorophenols, fluorohalophenols, N-acylfluoroanilines, and N-acylfluorohaloanilines | DOWELANCO (US) | 1992-02-12 | — | — | EP | claimed |
| EP-0331052-A2 | Process for the preparation of imidized acrylic polymers | ELF ATOCHEM ITALIA S.r.l. (IT) | 1989-09-06 | — | — | EP | claimed |
| EP-0315151-A2 | Process for the preparation of imidized acrylic polymers | ELF ATOCHEM ITALIA S.r.l. (IT) | 1989-05-10 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220274926-A1 | IMMUNOREGULATORY AGENTS | IDO1, IDO2, INMT | SMN1; SMN2 4584/4885HTT 3224/4885L3MBTL1 3766/4885 |
| US-20060058553-A1 | Novel bicyclic hydroxamates as inhibitors of histone deacetylase | HDAC1, HDAC2, HDAC11 | SMN1; SMN2 2943/4885HTT 293/4885L3MBTL1 2451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.