Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 20/20 | 0.54 |
| ▸ | CDK9 | P50750 | 20/20 | 0.54 |
| ▸ | CDK4 | P11802 | 7/20 | 0.45 |
| ▸ | CCND1 | P24385 | 7/20 | 0.45 |
| ▸ | CDK7 | P50613 | 3/20 | 0.45 |
| ▸ | CCNH | P51946 | 3/20 | 0.45 |
| ▸ | CDK2 | P24941 | 5/20 | 0.43 |
| ▸ | CCNA1 | P78396 | 5/20 | 0.43 |
| ▸ | CDK1 | P06493 | 4/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.42 |
| ▸ | CDK3 | Q00526 | 4/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.42 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26868496 | 0.85 | CCNT1 (0.53) | CCNT1CDK9CDK4CCND1CDK7 | |
| SCHEMBL26868498 | 0.85 | CCNT1 (0.53) | CCNT1CDK9CDK4CCND1CDK7 | |
| SCHEMBL14050765 | 0.85 | CCNT1 (0.53) | CCNT1CDK9CDK4CCND1CDK7 | |
| SCHEMBL26868453 | 0.85 | CCNT1 (0.53) | CCNT1CDK9CDK4CCND1CDK7 | |
| SCHEMBL12953323 | 0.84 | CCNT1 (0.43) | CCNT1CDK9CDK4CCND1CDK7 | |
| SCHEMBL14043130 | 0.83 | CCNT1 (0.48) | CCNT1CDK9CDK4CCND1CDK7 | |
| SCHEMBL26868787 | 0.82 | CCNT1 (0.50) | CCNT1CDK9CDK4CCND1CDK7 | |
| SCHEMBL26868322 | 0.82 | CCNT1 (0.50) | CCNT1CDK9CDK4CCND1CDK7 | |
| SCHEMBL26870912 | 0.82 | CCNT1 (0.50) | CCNT1CDK9CDK4CCND1CDK7 | |
| SCHEMBL26868692 | 0.82 | CCNT1 (0.50) | CCNT1CDK9CDK4CCND1CDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007044449-A2 | NOVEL PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS | SCHERING CORPORATION (US) | 2007-04-19 | — | — | WO | disclosed |