Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 10/20 | 0.57 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 7/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 6/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13121478 | 0.88 | GSK3B (0.74) | GSK3BCDK2CCNE1 | |
| SCHEMBL13289192 | 0.88 | GSK3B (0.59) | GSK3BCHEK1CDK2CCNE1CDK9 | |
| SCHEMBL14545821 | 0.86 | GSK3B (0.53) | GSK3BCHEK1CDK2CCNE1 | |
| SCHEMBL14418687 | 0.86 | GSK3B (0.56) | GSK3BCHEK1CDK2CCNE1 | |
| SCHEMBL13289494 | 0.84 | GSK3B (0.51) | GSK3BCHEK1CDK2 | |
| SCHEMBL13288641 | 0.84 | GSK3B (0.53) | GSK3BCHEK1CDK2CCNE1 | |
| SCHEMBL13288736 | 0.83 | GSK3B (0.53) | GSK3BCHEK1CDK2CCNE1 | |
| SCHEMBL13288716 | 0.82 | GSK3B (0.52) | GSK3BCHEK1CDK2CCNE1CDK9 | |
| SCHEMBL13289236 | 0.81 | GSK3B (0.48) | GSK3BCHEK1 | |
| SCHEMBL13289495 | 0.81 | GSK3B (0.48) | GSK3BCHEK1CDK2CCNE1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007044449-A2 | NOVEL PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS | SCHERING CORPORATION (US) | 2007-04-19 | — | — | WO | disclosed |